Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (07): 1068-1081.
李运波 ; 唐凤翔*; 孟 春; 郭养浩
Li, Yunbo ; Tang, Fengxiang*; Meng, Chun; Guo, Yanghao
Nipecotic acid and its derivatives, which have high bioactivity, are significant pharmaceutical intermediates. In this review, the synthetic methods of nipecotic acid and its derivatives are summarized. The application of nipecotic acid and its derivatives to synthesizing drugs for γ-aminobutyric acid (GABA) uptake inhibition, cancer chemotherapy, growth hormone secretion, anti-inflammation, cardiovascular disease Alzheimer’s disease, nootropics, anti-flu virus and bone disease is presented as well.
nipecotic acid derivative,
Li, Yunbo ; Tang, Fengxiang*; Meng, Chun; Guo, Yanghao. Progress in the Synthesis and Application of Nipecotic Acid and Its Derivatives[J]. Chin. J. Org. Chem., 2009, 29(07): 1068-1081.
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