Asymmetric reactinos of organosilicon compounds

Abstract

"Carbon-centered" chiral organosilicon compounds were synthesized and applied in asymmetric HosomiSakurai reactions and asymmetric reactions of α-silylallyl arbanions with aldehydes. Two aproaches for improving the stereoselectivities were suggested and examined. The asymmetric epoxidation reactions of alkenylsilanols were carried out, which enlarged the scope of Sharpless asymmetric epoxidation and provided a convenient route to simple optically active epoxide.

Key words: ORGANO SILICON COMPOUNDS, CHIRALITY, EPOXIDATION REACTION, ALLYL GROUP, SILANOL

CLC Number:

O627

Cite this article

Wang Dong. Asymmetric reactinos of organosilicon compounds[J]. Chin. J. Org. Chem., 2001, 21(11): 1090-1094.

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有机硅化合物的不对称合成反应