Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (11): 1345-1351. Previous Articles     Next Articles




  1. (华中科技大学化学系 武汉 430074)
  • 收稿日期:2006-05-08 修回日期:2006-08-11 发布日期:2007-10-20
  • 通讯作者: 龚跃法

Recent Advances in Kinetic Resolution UsingNon-Enzymatic Catalysts

SU Ning,ZHANG Fang-Lin,GONG Yue-Fa*   

  1. (Department of Chemistry, Huazhong University of Science and Technology, Wuhan 430074)
  • Received:2006-05-08 Revised:2006-08-11 Published:2007-10-20
  • Contact: GONG Yue-Fa

Kinetic resolution is one of the important synthetic methods to produce optically pure compounds. While a great progress was achieved in the domain of enzymatic kinetic resolution during the past years, non-enzymatic kinetic resolution is becoming another current hot area, which mainly refers to enanti-oselective acylation, oxidation, reduction, ring-opening, ring-closing, substitution and addition, etc. Recent advances in this field are briefly reviewed.

Key words: non-enzymatic catalysis, acylation, oxidation and reduction, ring opening and closing, kinetic resolution