Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (01): 27-42. Previous Articles     Next Articles

Review

抗癌活性天然产物Cryptophycins的研究进展

查慧艳,姚祝军*   

  1. (中国科学院上海有机化学研究所生命有机与天然产物化学国家重点实验室 上海 200032)
  • 收稿日期:2005-01-19 修回日期:2005-06-02 出版日期:2005-12-31 发布日期:2005-12-31
  • 通讯作者: 姚祝军

Studies on Natural Cryptophycins and Their Mimetics: A Review

ZHA Hui-Yan,YAO Zhu-Jun*   

  1. (State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemis-try,
    Chinese Academy of Sciences, Shanghai 200032)
  • Received:2005-01-19 Revised:2005-06-02 Online:2005-12-31 Published:2005-12-31
  • Contact: YAO Zhu-Jun

Cryptophycins are a family of naturally occurring macro-lactones with potent anticancer activities. Research progresses in the synthetic chemistry, structure-activity relationship and functional mimicking of cryptophycins are reviewed.

Key words: anticancer activity, ryptophycin, synthesis, mimetics, structure-activity relationship