Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (07): 1437-1450.DOI: 10.6023/cjoc201212016 Previous Articles     Next Articles



熊兴泉, 陈会新   

  1. 华侨大学材料科学与工程学院福建省高校功能材料重点实验室 厦门 361021
  • 收稿日期:2012-12-12 修回日期:2013-01-09 发布日期:2013-01-11
  • 通讯作者: 熊兴泉
  • 基金资助:

    国家自然科学基金(No. 21004024);福建省自然科学基金(No. 2011J01046);福建省“高校新世纪优秀人才支持计划”(No. 2012FJ-NCET-ZR03)和福建省“高校杰出青年科研人才培育计划”(No. 11FJPY02)资助项目.

Diels-Alder Cycloaddition Click Chemistry

Xiong Xingquan, Chen Huixin   

  1. Key Laboratory for Functional Materials of Fujian Higher Education, College of Materials Science and Engineering, Huaqiao University, Xiamen 361021
  • Received:2012-12-12 Revised:2013-01-09 Published:2013-01-11
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21004024), the Natural Science Foundation of Fujian Province (No. 2011J01046), the Program for New Century Excellent Talents in Fujian Province (No. 2012FJ-NCET-ZR03) and the University Distinguished Young Research Talent Training Program of Fujian Province (No. 11FJPY02).

Click reactions have rapidly become a new method for the synthesis of drugs, polymers and functional materials because of its high efficiency, high selectivity and reliable characteristics. With the further research of click reactions, the types of them are increasing continuously and the scope of application is also expanding at a fast rate. As an important reaction of click chemistry, Diels-Alder (D-A) reaction not only has high reaction efficiency, but also overcomes the shortcoming of using toxic heavy metal in the copper(I) catalyzed Cue-AAC reaction, so it provides a possible synthetic method for functional materials. Basing on the concept, characteristic and type of D-A reaction, this paper focuses upon the wide applications of D-A reaction in preparation of dendrimers, functional polymers and surface modification. Furthermore, the prospects of D-A reaction are also discussed.

Key words: Click chemistry, D-A reaction, functional polymers, surface modification, application