Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (2): 274-282.DOI: 10.6023/cjoc201509016 Previous Articles     Next Articles

Reviews

亚磷酰胺配体在铱催化不对称氢化反应中的应用 2017-2018 Awarded

袁乾家, 张万斌   

  1. 上海交通大学化学化工学院 上海 200240
  • 收稿日期:2015-09-13 修回日期:2015-10-13 出版日期:2016-02-25 发布日期:2015-10-23
  • 通讯作者: 张万斌 E-mail:wanbin@sjtu.edu.cn
  • 基金资助:

    国家自然科学基金(No. 21232004)和上海市优秀学科带头人(No. 14XD1402300)资助项目.

Applications of Phosphoramidite Ligands in Ir-Catalyzed Asymmetric Hydrogenation Reactions

Yuan Qianjia, Zhang Wanbin   

  1. School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240
  • Received:2015-09-13 Revised:2015-10-13 Online:2016-02-25 Published:2015-10-23
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21232004), and the Program of Shanghai Subject Chief Scientists (No. 14XD1402300).

Phosphoramidites, as a class of privileged chiral ligands, are suitable for different types of reactions, such as catalytic asymmetric hydrogenation, catalytic asymmetric allylic substitution, catalytic asymmetric Diels-Alder reaction and so on. Catalytic asymmetric hydrogenation reactions are some of the most important reactions in industry. In this review recent advances and applications of phosphoramidite ligands in Ir-catalyzed asymmetric hydrogenation of enamides and their derivatives, unfunctionalized enamines, imines and heteroaromatic compounds are discussed.

Key words: phosphoramidites, iridium, catalytic asymmetric hydrogenation