Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (3): 480-489.DOI: 10.6023/cjoc201508004 Previous Articles     Next Articles



熊兴泉, 韩骞, 石霖, 肖上运, 毕成   

  1. 华侨大学材料科学与工程学院 福建省高校功能材料重点实验室 厦门 361021
  • 收稿日期:2015-08-05 修回日期:2015-10-31 发布日期:2015-12-04
  • 通讯作者: 熊兴泉
  • 基金资助:

    国家自然科学基金(No. 21004024)、福建省自然科学基金(No. 2016J01063)、福建省高校新世纪优秀人才支持计划(No. 2012FJ-NCET-ZR03)和福建省高校杰出青年科研人才培育计划(No. 11FJPY02)以及华侨大学中青年教师科研提升资助计划(No. ZQN-YX103)资助项目.

Application of Deep-Eutectic Solvents in Green Organic Synthesis

Xiong Xingquan, Han Qian, Shi Lin, Xiao Shangyun, Bi Cheng   

  1. Key Laboratory for Functional Materials of Fujian Higher Education, College of Materials Science and Engineering, Huaqiao University, Xiamen 361021
  • Received:2015-08-05 Revised:2015-10-31 Published:2015-12-04
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21004024), the Natural Science Foundation of Fujian Province (No. 2016J01063), the Program for New Century Excellent Talents in Fujian Province (No. 2012FJ-NCET-ZR03), the University Distinguished Young Research Talent Training Program of Fujian province (No. 11FJPY02) and the Promotion Program for Young and Middle-aged Teacher in Science and Technology Research of Huaqiao University (No. ZQN-YX103).

Since the definition of "green chemistry" was proposed in 1991, the green solvents have attracted considerable attention. In the two decades ago, ionic liquids grew up. However, as following the research, it was found that ionic liquids had some drawbacks. Nowadays, some new types of low-transition-temperature mixtures, i.e. deep-eutectic solvents (DES) are raised. Compared with the traditional ionic liquids, deep-eutectic solvents are greener, cheaper and more accessible. Furthermore, the preparation methods of deep-eutectic solvents are easy, and the components of them are biodegradable. In recent years, deep-eutectic solvents have been applied as green solvents in organic synthesis widely. In this review, the application of deep-eutectic solvents in cyclization reactions, replacement reactions, addition reactions, multicomponent reactions, enzyme catalytic reactions and other reactions in the last few years are briefly summarized, and the prospects of DESs are also discussed.

Key words: deep-eutectic solvents, green chemistry, organic synthesis, catalysis