Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (9): 2053-2074.DOI: 10.6023/cjoc201604002 Previous Articles     Next Articles

REVIEW

苦味酸检测用有机荧光探针的分子设计与合成研究进展

曹梁a, 熊金锋b, 吴彦城a, 丁沙a, 李铭冰a, 谢芬a, 马志晗a, 汪朝阳a   

  1. a 华南师范大学化学与环境学院 教育部环境理论化学重点实验室 广州 510006;
    b 广东东阳光药业研究院 东莞 523871
  • 收稿日期:2016-04-01 修回日期:2016-04-26 发布日期:2016-05-19
  • 通讯作者: 汪朝阳 E-mail:wangzy@scnu.edu.cn
  • 基金资助:

    广东省自然科学基金(No.2014A030313429)、广州市科技计划科学(技术)研究专项(No.201607010251)、华南师范大学大创计划(No.20161528)资助项目.

Progress in the Molecular Design and Synthesis of Organic Fluorescent Probe for Picric Acid Detection

Cao Lianga, Xiong Jinfengb, Wu Yanchenga, Ding Shaa, Li Mingbinga, Xie Fena, Ma Zhihana, Wang Zhaoyanga   

  1. a Key Laboratory of Theoretical Chemistry of Environment, Ministry of Education, School of Chemistry and Environment, South China Normal University, Guangzhou 510006;
    b HEC Pharm R & D Center, Dongguan 523871
  • Received:2016-04-01 Revised:2016-04-26 Published:2016-05-19
  • Supported by:

    Project supported by the Natural Science Foundation of Guangdong Province (No.2014A030313429), the Guangzhou Science and Technology Project Scientific Special (General Items, No.201607010251) and the Undergraduates Innovation Project of South China Normal University (No.20161528).

Highly selective and sensitive detection of nitro aromatic explosive picric acid (PA) has become a challenging task due to the increasing concerns over national security and environmental awareness. In order to adjust to the trend of green chemistry, more and more attention has been attached to the fluorescent probes among various PA detection techniques, especially the organic molecule fluorescent probes without any metal ion (e.g. Hg2+)-assisted fluorescence enhancement for their easy availability and good processability. According to the molecular composition of the probes, these organic molecule probes can be classified into three categories as polymer, oligomer, and small molecule type. The progress on their molecular design and synthesis is reviewed, and their future trend is also prospected.

Key words: picric acid, organic fluorescent probe, molecular design, synthesis, detection mechanism