Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (7): 1837-1845.DOI: 10.6023/cjoc201902006 Previous Articles     Next Articles

Reviews

高价碘试剂的有机电化学合成及应用研究进展

张怀远, 唐蓉萍, 石星丽, 颉林, 伍家卫   

  1. 兰州石化职业技术学院应用化学工程学院 甘肃省石油化工过程工程应用技术协同创新中心 兰州 730060
  • 收稿日期:2019-02-11 修回日期:2019-03-10 出版日期:2019-07-25 发布日期:2019-04-09
  • 通讯作者: 张怀远 E-mail:zhanghuaiyuan@lzpcc.edu.cn
  • 基金资助:

    甘肃省高等学校科学研究(No.2018B-091)和兰州石化职业技术学院教科研(No.JY2018-25)资助项目.

Recent Advances in Organic Electrochemical Synthesis and Application of Hypervalent Iodine Reagents

Zhang Huaiyuan, Tang Rongping, Shi Xingli, Xie Lin, Wu Jiawei   

  1. Gansu Province Collaborative Innovation Center of Petrochemical Engineering Application Technology, College of Applied Chemical Engineering, Lanzhou Petrochemical Polytechnic, Lanzhou 730060
  • Received:2019-02-11 Revised:2019-03-10 Online:2019-07-25 Published:2019-04-09
  • Contact: 10.6023/cjoc201902006 E-mail:zhanghuaiyuan@lzpcc.edu.cn
  • Supported by:

    Project supported by the Scientific Research Projects of Colleges and Universities in Gansu Province (No. 2018B-091) and the Teaching and Scientific Research Project of Lanzhou Petrochemical Poly Technic (No. JY2018-25).

Anodic oxidation of aryl iodine compouds is a green and efficient method for the synthesis of hypervalent iodine reagents. This method replaces chemical reagents with electric current, avoiding the use of expensive and handle difficult oxidants such as m-CPBA, H2O2, oxone, selectfluor etc. Electrochemically generated hypervalent iodine reagents can not only promote fluorination, oxidative cyclization, but also be successfully applied in the total synthesis of natural products. In addition, recyclable aryl iodine mediator can be used to indirect anodic fluorination and easily separated from products. The organic electrochemical synthesis of hypervalent iodine reagents and their applications in various chemical transformations are reviewed.

Key words: electrochemical synthesis, hypervalent iodine reagent, fluorination, oxidative cyclization