Chinese Journal of Organic Chemistry ›› 2022, Vol. 42 ›› Issue (3): 803-811.DOI: 10.6023/cjoc202109049 Previous Articles     Next Articles



吴绵园a,b, 喻艳超a,*(), 刘洋a, 由君a,*(), 武文菊a, 刘波a   

  1. a 哈尔滨理工大学材料科学与化学工程学院 绿色化工技术黑龙江省高校重点实验室 哈尔滨 150080
    b 黑龙江省科学院石油化学研究院 哈尔滨 150040
  • 收稿日期:2021-09-29 修回日期:2021-10-28 发布日期:2021-11-25
  • 通讯作者: 喻艳超, 由君
  • 基金资助:
    国家自然科学基金(21908034); 黑龙江省自然科学基金(LH2021H001)

Synthesis and Application of a Novel Fluorescent Probe for Sequential Recognition Cu2+ and Glyphosate

Mianyuan Wua,b, Yanchao Yua(), Yang Liua, Jun Youa(), Wenju Wua, Bo Liua   

  1. a Key Laboratory of Green Chemical Engineering and Technology of College of Heilongjiang Province, College of Materials Science and Chemical Engineering, Harbin University of Science and Technology, Harbin 150080
    b Institute of Petrochemistry, Heilongjiang Academy of Sciences, Harbin 150040
  • Received:2021-09-29 Revised:2021-10-28 Published:2021-11-25
  • Contact: Yanchao Yu, Jun You
  • Supported by:
    National Natural Science Foundation of China(21908034); Natural Science Foundation of Heilongjiang Province(LH2021H001)

A novel fluorescent probe L based on coumarin-derived acylhydrazone was designed and synthesized by using 7-(4-methoxyphenyl)ethynyl coumarin as report group. The probe L showed high selectivity and good anti-interference ability towards Cu2+ ion through the color of solution changed from light brown to yellow for naked-eye detection and significant fluorescence intensity quenched in the dimethyl sulfoxide (DMSO)/H2O [V:V=7:3, 2-[4-(2-hydroxyethyl)piperazin-1- yl]ethanesulfonic acid (HEPES) 10 mmol/L, pH=7.4] solution, and the detection limit of probe L to Cu2+ could reach 5.6×10–8 mol/L. Meanwhile, the L-Cu2+ system has high selectivity, good sensitivity, wide pH range (5~9) and low detection limit (11.3 ng/mL) for the detection of glyphosate by ligand replacement method. In addition, glyphosate detection was assessed within the actual water samples for testing the L-Cu2+actual application and the method was expected to the detection in environmental samples.

Key words: coumarin-derived acylhydrazone, fluorescent probe, sequential recognition, glyphosate