Acta Chimica Sinica ›› 2012, Vol. 70 ›› Issue (06): 747-752.DOI: 10.6023/A1109301 Previous Articles     Next Articles

Special Topic


李华春a, 覃明丽a,b, 谭克俊a   

  1. a 发光与实时分析教育部重点实验室 西南大学化学化工学院 重庆 400715;
    b 南充农产品质量监测检验中心 南充 637000
  • 投稿日期:2011-09-30 修回日期:2011-12-03 发布日期:2012-01-31
  • 通讯作者: 谭克俊
  • 基金资助:

    国家自然科学基金(No. 20877063)和西南大学大型仪器设备开放基金(No. 201133)资助项目.

Study on Spectra of Interaction between Silicotungstic Acid and Palmatine Hydrochloride and Its Analysis Application

Li Huachuna, Qin Minglia,b, Tan Kejuna   

  1. a Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715;
    b Nanchong Municipal Monitoring and Testing Center for Agricultural Product Quality, Nanchong 637000
  • Received:2011-09-30 Revised:2011-12-03 Published:2012-01-31
  • Supported by:

    Project was supported by the National Natural Science Foundation of China (No. 20877063) and the Large Instruments Open Foundation of Southwestern University (No. 201133).

A novel resonance light scattering (RLS) method for the determination of palmatine hydrochloride (PaH) has been developed based on the largely enhanced RLS signals at 297 nm due to the interaction between Silicotungstic acid (STA) and PaH by electrostatic force in the pH 0.91 HCl-NaOAc medium. The linear range of PaH is 0.09~3.2 μg/mL. The limit of detection (LOD) is 9.1 ng/mL. In this work, the effects of pH and ionic strength on interaction were investigated. At the same time, the UV spectra, the fluorescence spectra and the reaction mechanism of system were also investigated. This method has been applied successfully for the determination of PaH in pharmaceutical and blood serum samples with RSD≤4.2%.

Key words: resonance light scattering, palmatine hydrochloride, silicotungstic acid