Studies on the chemical constituents of clausena lansium(lour.) Skeels II: The isolation and structural elucidation of neoclausenamide and cycloclausenamide

Acta Chimica Sinica ›› 1987, Vol. 45 ›› Issue (12): 1170-1174. Previous Articles Next Articles

Original Articles

黄皮叶化学成分的研究II: 两个新的环酰胺化合物的结构

杨明河;陈延镛;黄量

中国医学科学院药物研究所

发布日期:1987-12-15

Studies on the chemical constituents of clausena lansium(lour.) Skeels II: The isolation and structural elucidation of neoclausenamide and cycloclausenamide

YANG MINGHE;CHEN YANYONG;HUANG LIANG

Published:1987-12-15

Abstract

Two novel lactams, neoclausenamide (I) and cycloclausenamide (II), were identified from the leaves of C. lansium. I and II decreased the level of serum glutamate pyruvate transaminase in mice treated with CCl4 (liver-damaging agent).

Key words: DRUGS, CHEMICAL COMPOSITION, X-RAY DIFFRACTION ANALYSIS, PROTON MAGNETIC RESONANCE SPECTROMETRY, HEPATITIS, LACTAM, BRIDGE COMPOUNDS, PYRROLIDONE P, CLAUSENA, CLAUSENAMIDE

CLC Number:

O629

Cite this article

YANG MINGHE;CHEN YANYONG;HUANG LIANG. Studies on the chemical constituents of clausena lansium(lour.) Skeels II: The isolation and structural elucidation of neoclausenamide and cycloclausenamide[J]. Acta Chimica Sinica, 1987, 45(12): 1170-1174.

[1]	Tongyi Zhai, Chang Ge, Pengcheng Qian, Bo Zhou, Longwu Ye. Brønsted Acid-Catalyzed Intramolecular Hydroalkoxylation/Claisen Rearrangement of Ynamides^★ [J]. Acta Chimica Sinica, 2023, 81(9): 1101-1107.
[2]	Pei Qin, Hai Ma, Fa-Guang Zhang, Jun-An Ma. Synthesis of 6-CF₃-1,2,4-triazine-based Tyrosine Kinase Inhibitors and The Evaluation of Biological Activities^★ [J]. Acta Chimica Sinica, 2023, 81(7): 697-702.
[3]	Xueyang Yin, Kai Gu, Zhengzhong Shao. Preparation of the Protein/Polyphenylboronic Acid Nanospheres for Drug Loading and Unloading [J]. Acta Chimica Sinica, 2023, 81(2): 116-123.
[4]	Zhang Xiaolei, Tian Gan, Zhang Xia, Wang Qing, Gu Zhanjun. Controlled Release of Carbon Monoxide Based on Nanomaterials and Their Biomedical Applications [J]. Acta Chim. Sinica, 2019, 77(5): 406-417.
[5]	Zhou Rendan, Li Laisheng, Cheng Biaoping, Nie Guizhen, Zhang Hongfu. Preparation and Evaluation of a Novel bis(β-cyclodextrin)-bonded SBA-15 Chiral Stationary Phase for HPLC [J]. Acta Chimica Sinica, 2014, 72(6): 720-730.
[6]	Yang Wenhua, Yu Shuying, Chen Sheng, Liu Yezhuo, Shao Zhengzhong, Chen Xin. Doxorubicin-Loaded Silk Fibroin Nanospheres [J]. Acta Chimica Sinica, 2014, 72(11): 1164-1168.
[7]	Wang Kang, Wang Hailong, Mack John, Li Wenjun, Kobayashi Nagao, Jiang Jianzhuang. Chiral Phthalocyanine with Unambiguous Absolute Molecular Structures for Both Enantiomers [J]. Acta Chimica Sinica, 2012, 70(17): 1791-1797.
[8]	LI Qing-Lin, XU Cheng-Tai, HE Shi-Wei, YAO Zheng-Quan. Line Scanning Analysis of Distributing Mode of Chemical Composition in Reaction Layer of Jun Porcelain [J]. Acta Chimica Sinica, 2011, 69(08): 912-918.
[9]	. Resonance Rayleigh Scattering Spectra of Rifamycins Antibiotics-Cu(II)-Nnucleic Acid System [J]. Acta Chimica Sinica, 2008, 66(19): 2131-2137.
[10]	LI Bo-Nan; LIANG Yong; JIAO Lei; HU Li-Bo; DU Da-Ming; XU Jia-Xi*. Synthesis and Stereochemistry of 3-(Thiophen-2-yl)-β-lactams [J]. Acta Chimica Sinica, 2007, 65(16): 1643-1648.
[11]	GUO Wen-Sheng*,GUO Fang,WU Xue-Dong,TONG Jian,WANG Zhong-Hua. Role of CH/π, CH/O Weak Hydrogen Bonds in Constructing Inclusion Compounds of 2,6-Bis(α-phenylbenzyl)-1,5-naphthalenediol [J]. Acta Chimica Sinica, 2005, 63(16): 1525-1530.
[12]	CHENG Qiong, PENG Tu-Zhi, LIU Ai-Li. Detection of Hepatitis B Surface Antigen Using Immunovoltammetry with Nano-Magnetic Microsphere [J]. Acta Chimica Sinica, 2004, 62(24): 2447-2450.
[13]	Song Yumin;Yang Peiju;Wang Liufang;Yang Meiling;Kang Jingwan. Study on the Interactions between Sm(RA)_2·Ac·4H_2O and DNA [J]. Acta Chimica Sinica, 2003, 61(8): 1266-1270.
[14]	Yao Chunsuo;Lin Mao;Liu Xin;Wang Yinghong. Stilbenes from Gnetum cleistostachyum [J]. Acta Chimica Sinica, 2003, 61(8): 1331-1334.
[15]	高莹;Han Xiaofeng;Liu Ying;Gao Ying;Lai Luhua. Comparative Molecular Field Analysis of Non-peptidic Inhibitors of Thrombin [J]. Acta Chimica Sinica, 2003, 61(7): 1136-1136.

黄皮叶化学成分的研究II: 两个新的环酰胺化合物的结构

Studies on the chemical constituents of clausena lansium(lour.) Skeels II: The isolation and structural elucidation of neoclausenamide and cycloclausenamide

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments