Synthesis of 1-(4-piperidino-phenyl)-3-amide-4-substituted phenyl- α-oxo-azetidine methoiodies

Acta Chimica Sinica ›› 1990, Vol. 48 ›› Issue (12): 1212-1215. Previous Articles Next Articles

Original Articles

1-(4'哌啶苯基)-3-酰氨基-4-取代苯基α-氧吖丁啶甲碘化物的合成

尹述凡;毛文仁

华西医科大学药学院

发布日期:1990-12-15

Synthesis of 1-(4-piperidino-phenyl)-3-amide-4-substituted phenyl- α-oxo-azetidine methoiodies

YIN SHUFAN;MAO WENREN

Published:1990-12-15

Abstract

Title compounds I [R = PhCH2, 4-ClC6H4OCH2, PhOCH2, 5-methyl-4-(2-chlorophenyl)-4-isoxazolyl, 5-methyl-3-phenyl-4-isoxazolyl; R1 = 3,4-methylenedioxyphenyl, Ph, 4-ClC6H4] were prepared via cycloaddn. of (benzylideneaminophenyl)piperidines II with Dane salt. I showed b-lactamase inhibitor activity.

Key words: PIPERIDINE P, INFRARED SPECTROPHOTOMETRY, ELEMENTAL ANALYSIS, MASS SPECTROGRAPHY, BENZENE P, IODIDE, PROTON MAGNETIC RESONANCE SPECTROMETRY, LACTAM, OXYGEN COMPOUNDS, QUATERNARY AMMONIUM COMPOUNDS

CLC Number:

O621
R914

Cite this article

YIN SHUFAN;MAO WENREN. Synthesis of 1-(4-piperidino-phenyl)-3-amide-4-substituted phenyl- α-oxo-azetidine methoiodies[J]. Acta Chimica Sinica, 1990, 48(12): 1212-1215.

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1-(4'哌啶苯基)-3-酰氨基-4-取代苯基α-氧吖丁啶甲碘化物的合成

Synthesis of 1-(4-piperidino-phenyl)-3-amide-4-substituted phenyl- α-oxo-azetidine methoiodies

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