Acta Chimica Sinica ›› 2008, Vol. 66 ›› Issue (10): 1235-1238. Previous Articles     Next Articles

Original Articles

玉米须中的一个新黄酮和两个尿素苷

徐燕*,1,2,梁敬钰2,邹忠梅1,杨峻山1   

  1. (1中国医学科学院中国协和医科大学药用植物研究所 北京 100094)
    (2中国药科大学天然药化教研室 南京 210009)
  • 投稿日期:2007-10-09 修回日期:2007-12-12 发布日期:2008-05-28
  • 通讯作者: 徐燕

A Novel Flavone and Two Urea Glycosides from the Style of Zea mays L.

XU, Yan*,1,2, LIANG, Jing-Yu2, ZOU, Zhong-Mei1, YANG, Jun-Shan1   

  1. (1 Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094)
    (2Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009)
  • Received:2007-10-09 Revised:2007-12-12 Published:2008-05-28
  • Contact: XU, Yan

The style of Zea mays L. is a kind of traditional Chinese medicine, which has many biological activities and has been used in folk medicine. To study its bioactive constituents, the style of Zea mays L. was subjected to phytochemical investigation resulting in the isolation of a novel flavone (1) and two urea glycosides (2 and 3). Their structures were determined by various spectroscopic data, including 1H NMR, 13C NMR, HSQC, HMBC, 1H-1H COSY and ESI-MS. Compound 1 was a novel flavone and elucidated as 6-acetyl-luteolin. Compounds 2 and 3 were two novel natural products and identified as rhamnosyl urea and 1,3-dirhamnosyl urea respectively. The 1H NMR and 13C NMR spectra data of compounds 2 and 3 were assigned for the first time.

Key words: the style of Zea mays L., 6-acetyl-luteolin, rhamnosyl urea, 1,3-dirhamnosyl urea