Acta Chimica Sinica ›› 2007, Vol. 65 ›› Issue (16): 1679-1684. Previous Articles     Next Articles

Original Articles

短柄雪胆中的三萜葫芦素及其皂苷

陈剑超, 张重权, 邱明华*   

  1. (中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室 昆明 650204)
  • 投稿日期:2007-03-27 修回日期:2007-06-03 发布日期:2007-08-28
  • 通讯作者: 邱明华

Chemical Constituents from the Tubers of Hemsleya delavayi

CHEN Jian-Chao; ZHANG Zhong-Quan; QIU Ming-Hua*   

  1. (State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204)
  • Received:2007-03-27 Revised:2007-06-03 Published:2007-08-28
  • Contact: QIU Ming-Hua

Fourteen cucurbitane compounds, including five new ones named delavanosides A~E (15), and nine known ones identified as carnosiflogenin A (6), scandenoside R8 (7), carnosifloside I (8), carnosifloside II (9), carnosifloside III (10), hemslecin A (11), hemslecin B (12), 2-O-β-D-glycoside of hemslecin A (13) and scandenoside R1 (14), were isolated from the tubers of Hemsleya delavayi. On the basis of spectral analysis and chemical methods, the new compounds were elucidated as 3β,27-dihydroxycucurbita-5,24-dien- 11-on-27-O-β-D-glucopyranosyl(1®2)-β-D-glucopyranoside (1), 3β,20,27-trihydroxycucurbita-5,24-dien- 11-on-27-O-β-D-glucopyranosyl(1®2)-b-D-glucopyranoside (2), 3β,20,27-trihydroxycucurbita-5,24-dien- 11-on-3-O-β-D-glucopyranosyl-27-O-β-D-glucopyranosyl(1®2)-β-D-glucopyranoside (3), 3β,26-dihydroxy- cucurbita-5,24-dien-11-on-3-O-β-D-glucopyranoside (4) and 3β,26-dihydroxycucurbita-5,24-dien-11-on-3- O-β-D-glucopyranosyl-26-O-β-D-glucopyranosyl(1®6)-β-D-glucopyranosyl(1®2)-β-D-glucopyranoside (5). Compound 6 was also firstly isolated as a natural product.

Key words: Hemsleya delavayi, Cucurbitaceae, delavanoside A~E, cucurbitane compound