A poly[(dimethylamino)ethyl methacrylate]-block-poly(ε-caprolactone) copolymer (PDMAEMA- b-PCL) bearing a sugar moiety at the PDMAEMA end was synthesized via a sequential anionic polymerization of dimethylamino ethyl methacrylate (DMAEMA) and ε-caprolactone (ε-CL), followed by a coupling reaction with D-gluconolactone. The structure of the polymer was confirmed by ¹H NMR spectroscopy, IR and gel permeation chromatography. The self-assembly behavior of this polymer in aqueous solution was studied by using dynamic light scattering.

Key words: G-PDMAEMA-b-PCL, anionic polymerization, amphiphilic diblock copolymer