Acta Chimica Sinica ›› 1998, Vol. 56 ›› Issue (4): 335-339. Previous Articles     Next Articles

Original Articles

可控组装方法制备脂质体

张林刚;胡继存;陆祖宏   

  1. 东南大学分子与生物分子电子学实验室
  • 发布日期:1998-04-15

Preparation of liposomes by a controlled assembling method

ZHANG LINGANG;HU JICUN;LU ZUHONG   

  • Published:1998-04-15

A method of liposome preparation is demonstrated, which includes two experimental steps: (a)water in oil(W/O) microemulsion are prepared by sonication; (b)water droplets in the W/O microemulsion pass through the monolayer at the oil-water interface by centrifugation and transform into liposomes. Sizes of liposomes are 50-200nm in diameter. The percentage capture reached 57% and no leakage of encapsulated content was observed during the preparation.

Key words: LIPOSOME, MICROEMUSION

CLC Number: