Investigation on the Interaction between Quaternary Ammonium Surfactants and Lecithin Vesicles

Acta Chimica Sinica ›› 2005, Vol. 63 ›› Issue (6): 450-454. Previous Articles Next Articles

Original Articles

季铵盐表面活性剂与卵磷脂囊泡相互作用的研究

张春艳，徐晓明，吴章锋，韩国彬*

(厦门大学化学系固体表面物理化学国家重点实验室厦门 361005)

投稿日期:2004-07-14 修回日期:2004-11-26 发布日期:2010-12-10
通讯作者: 韩国彬

Investigation on the Interaction between Quaternary Ammonium Surfactants and Lecithin Vesicles

ZHANG Chun-Yan, XU Xiao-Ming, WU Zhang-Feng, HAN Guo-Bin*

(Department of Chemistry, State Key Laboratory for Physical Chemistry of Solid Surface, Xiamen University, Xiamen 361005)

Received:2004-07-14 Revised:2004-11-26 Published:2010-12-10
Contact: HAN Guo-Bin

Abstract

The solubilization process of quaternary ammonium surfactants within lecithin vesicles has been studied by means of optical density monitoring, dynamic light scattering (DLS) and ζ-potential. To C₁₂-8-C₁₂•2Br-liposome system, the vesicle-to-micelle structure transition occurred within 6 h, and could be described by a simple three-stage model. While the DTAB-liposome system remained vesicle state even after 48 h. The size of total volume of hydrophilic head group (V_head) as the main influencing factor was investigated.

Key words: quaternary ammonium surfactant, liposome, solubilization process, dynamic light scattering, ζ-potential

Cite this article

ZHANG Chun-Yan, XU Xiao-Ming, WU Zhang-Feng, HAN Guo-Bin*. Investigation on the Interaction between Quaternary Ammonium Surfactants and Lecithin Vesicles[J]. Acta Chimica Sinica, 2005, 63(6): 450-454.

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季铵盐表面活性剂与卵磷脂囊泡相互作用的研究

Investigation on the Interaction between Quaternary Ammonium Surfactants and Lecithin Vesicles

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