Acta Chimica Sinica ›› 2011, Vol. 69 ›› Issue (06): 739-744. Previous Articles     Next Articles

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柚皮苷印迹β-环糊精聚合物的制备及性能研究

马秀玲1,陈巧平2,兰瑞芳1,郑曦1,陈晓1,陈震*,1,2   

  1. (1 福建师范大学化学与材料学院 福州 350007)
    (2宁德师范高等专科学校化学系 宁德 352100)
  • 收稿日期:2010-06-02 修回日期:2010-11-01 出版日期:2011-03-28 发布日期:2010-11-26
  • 通讯作者: 陈震 E-mail:zc1224@pub1.fz.fj.cn

Preparation and Property Studies of Naringin Imprinting β-Cyclodextrin Polymer

Ma Xiuling1 Chen Qiaoping 2 Lan Ruifang1 Zheng Xi1 Chen Xiao1 Chen Zhen*,1,2   

  1. (1 College of Chemistry and Materials Science, Fujian Normal University, Fuzhou 350007)
    (2 Chemistry Department of Fujian Ningde Teachers College, Ningde 352100)
  • Received:2010-06-02 Revised:2010-11-01 Online:2011-03-28 Published:2010-11-26

Rod-like molecularly imprinted polymer (RMIP) was prepared by emulsion polymerization using β-cyclodextrin (β-CD) as a functional polymer, naringin (NG) as a template molecule and hexamethylene diisocyanate (HMDI) as crosslinker. The morphology, pore size distribution and specific surface area of the RMIP were observed by means of scanning electron microscopy (SEM) and BET adsorption apparatus. The interaction between the template molecule and functional polymer was analyzed by the infrared spectrum (IR) and 1H-nuclear magnetic resonance (1H NMR). Its adsorption property and selectivity were evaluated by equilibrium adsorption experiment method. The obtained results revealed appropriate affinity and selectivity of RMIP to NG. Scatchard analysis suggests that during RMIP recognition of NG, there were two classes of binding sites. The calculated dissociation constant KD1 and apparent maximum number Bmax1 of binding sites with high affinity were 0.016 mmol/L and 15.31 μmol/g respectively, while KD2 and Bmax2 of binding sites with low affinity were 0.24 mmol/L and 98.41 μmol/g. In 0.02 mg/mL NG solution, the distribution coefficients KD of NG on RMIP and corresponding NIP are 4.38 and 2.86, respectively. The imprinting factor α is 1.53.

Key words: molecularly imprinted polymer, naringin, molecular recognition, β-cyclodextrin