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Acta Chimica Sinica ›› 1964, Vol. 30 ›› Issue (2): 205-210. Previous Articles     Next Articles

肽的研究Ⅳ.带保护基的牛胰岛素A链羧基末端十二肽及十六肽的合成

汪猷, 屠传忠, 陆熙炎, 张伟君, 王志勤, 汤永禔, 陈毓群   

  1. 中国科学院有机化学研究所
  • 投稿日期:1963-09-17 发布日期:2013-06-03

STUDIES ON PEPTIDES Ⅳ. SYNTHESIS OF PROTECTED C-TERMINAL DODEDECA- AND HEXADECAPEPTIDE OF THE A-CHAIN OF BOVINE INSULIN

WANG YU, TU CHUAN-TSUNG, LOH HSI-YIEN, CHANG WEI-CHUN, WANG CHIK-CHIN, CHEN YOH-CHONG, TANG YUNG-TI   

  1. Institute of Organic Chemistry, Academia Sinica
  • Received:1963-09-17 Published:2013-06-03

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Two protected C-terminal peptides of tile A-chain of bovine insulin have been synthesized.They are dodecapeptide Ⅰ (N-carbobenzoxy-L-valyl-S-benzyl-L-cysteinyl-L-seryl-L-leucyl-L-tyrosyl-L-glutaminyl-L-leucyl-y-methyl-L-glutamyl-L-asparaginyl-L-tyrosyl-S-benzyl-L-cysteinyl-L-asparagine methyl ester and hexadecapeptide Ⅱ (N-carbobenzoxy-S-benzyl-L-cysteinyl-S-benzyl-L-cysteinyl-L-alanyl-L-Beryl-L-valyl-S-benzyl-L-cysteinyl-L-seryl-L-leucyl-L-tyrosyl-L-glutaminyl-L-leucyl-y-methyl-L-glutamyl-L-asparaginyl-L-tyrosyl-S-benzyl-L-cysteinyl-L-asparagine methyl ester).