Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (10): 1812-1826.DOI: 10.6023/cjoc1202041 Previous Articles     Next Articles



李仲振a, 丁宁b, 张伟b, 王鹏a, 李明a, 李英霞b   

  1. a 中国海洋大学医药学院 教育部海洋药物重点实验室 青岛 266003;
    b 复旦大学药学院 上海 201203
  • 收稿日期:2012-02-04 修回日期:2012-04-20 发布日期:2012-05-21
  • 通讯作者: 丁宁
  • 基金资助:

    国家自然科学基金(Nos. 81072525, 21002014)、教育部博士点新教师基金(No. 20100071120051)、中央高校专项基金(No. 10FX061)资助项目.

Progress in the Chemical Synthesis of 2-Deoxy-glycosides

Li Zhongzhena, Ding Ningb, Zhang Weib, Wang Penga, Li Minga, Li Yingxiab   

  1. a Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003;
    b School of Pharmacy, Fudan University, Shanghai 201203
  • Received:2012-02-04 Revised:2012-04-20 Published:2012-05-21
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 81072525, 21002014), the Research Fund for the Doctoral Program of Higher Education of China (No. 20100071120051), and the Fundamental Research Funds for the Central Universities (No. 10FX061).

2-Deoxy-glycosides are monosaccharides in which the hydroxyl group at C-2 is replaced with a hydrogen atom. They exist widely in natural products and show various bioactivity. The recent advances in organic synthesis of 2-deoxy-glycosides are summarized mainly focusing on direct etherification, direct glycosidic bond formation, temporary protecting groups, synthesis from non-sugar and so on.

Key words: 2-deoxy-glycosides, oligosaccharides, chemosynthesis methodology