Chinese Journal of Organic Chemistry 2026, 46(6)

- About the Cover:
  
  Machine learning bridges molecular structures and sur-factant performance. The advances in machine learning for predicting key surfactant properties (e.g., critical micelle concentration, surface tension, hydrophilic-lipo- philic balance, adsorption efficiency, and Krafft point) are systematically reviewed by Zhang, Ding, Guo, Li, and Xue on page 2310. Furthermore, preliminary applications and prospects of this technology in predicting environmental safety parameters such as biodegradability and ecotoxicity are examined.
- About the Cover:
  
  The selective anion recognition of pyridinebisthiazola-mine-strapped calix[4]pyrrole 2 is reported by Yan, Huo and He on page 2442. This receptor strongly binds H₂PO₄^- via simultaneous proton transfer between its thiazole units and H₂PO₄^-. Relying on pH-responsive protonation-deprotonation of the bridging strap, the macrocycle serves as a pH-tunable molecular switch, selectively trapping H₂PO₄^- under neutral conditions and switching its binding affinity to H₂PO₄^- in acidic media.
- About the Cover:
  
  The X—H (X＝O, N, S) bond insertion reaction catalyzed by bismuth for diaryl diazomethanes is reported by Lü, Liu, Liu, Si, Li, Chen, and Liu on page 2409. This reaction is applicable to various compounds containing X—H bonds. This method has the characteristics of simple operation, mild conditions, and wide substrate range, providing an alternative solution for reactions involving transition metals and expanding the application of bismuth metal in carbene chemistry.
2026, 46(6)

25 June 2026
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REVIEWS ARTICLES HIGHLIGHTS

REVIEWS

Advances in Asymmetric Double (Transfer) Hydrogenation of Conjugated Enones

Guanbao Qin, Menglong Zhao, Zhaobin Han, Kuiling Ding

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2163-2176 DOI: 10.6023/cjoc202603008

Abstract( 124) HTML( 2) PDF(990KB)( 104 )

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Recent Advances in the Light-Driven One-Step Synthesis of Dual Carbon-Substituted Bicyclo[1.1.1]pentanes

An Chen, Zeyi Wang, Wanmei Li, Jun Xu

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2177-2192 DOI: 10.6023/cjoc202601034

Abstract( 84) HTML( 2) PDF(738KB)( 24 )

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Advances in the Asymmetric Synthesis of the Potent Neurotoxin Anatoxin-a

Mei Dong, Guo-Qiang Lin, Ran Hong, Sha-Hua Huang, Changmin Xie

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2193-2206 DOI: 10.6023/cjoc202601017

Abstract( 93) HTML( 1) PDF(1318KB)( 59 )

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Recent Advances in Deuterium Functionalization Reactions of Alkenes and Alkynes

Mingyue Fu, Zhan Dong, Wei Chen, Tie-Gen Chen

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2207-2226 DOI: 10.6023/cjoc202602008

Abstract( 107) HTML( 2) PDF(1193KB)( 66 )

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Research Progress in Synthesis and Application of 3-Cyanopyridines

Guiyuan Chen, Shengyu Li, Jilin Guo, Xiang Wang, Yetong Liu, Beining Xiao, Zhaoyang Wang

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2227-2240 DOI: 10.6023/cjoc202512034

Abstract( 172) HTML( 2) PDF(843KB)( 117 )

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Research Progress on Reductive Defluorination of Polytetrafluoroethylene (PTFE)

Xiong She, Hao Cui, Xiao Zhang

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2241-2248 DOI: 10.6023/cjoc202601015

Abstract( 41) HTML( 3) PDF(633KB)( 15 )

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Progress in Organothorium Bipyridyl Complexes

Yi Heng, Xiaoying Cao, Yuncan Dou, Dongwei Wang, Pikun Yang, Guofu Zi

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2249-2266 DOI: 10.6023/cjoc202601002

Abstract( 29) HTML( 0) PDF(744KB)( 22 )

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Advances in the Asymmetric Synthesis of Chiral Fragrance (–)-Menthol

Rucan Liu, Jie Tang, Lijun Zhu, Ming Ma, Xudong Hu, Wenbo Liu

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2267-2274 DOI: 10.6023/cjoc202512024

Abstract( 102) HTML( 2) PDF(646KB)( 69 )

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Recent Progress in C—H Functionalization of N-Sulfonyl Ketimines

Jinfeng Shang, Hongtao Ji, Jiayao Huang, Rongqiang Li

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2275-2309 DOI: 10.6023/cjoc202512014

Abstract( 79) HTML( 4) PDF(1488KB)( 42 )

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Research Progress of Machine Learning in Surfactant Performance Prediction and Design

Guiping Zhang, Changhua Ding, Yong Guo, Yao Li, Xiaosong Xue

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2310-2326 DOI: 10.6023/cjoc202512023

Abstract( 77) HTML( 1) PDF(7106KB)( 53 )

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Research Progress in the Synthesis of 1,3-Benzoxazine via Radical Cascade Reaction

Dong Yan, Weibao He, Yucai Tang, Cui Xin, Zi Yang, Xiang Chen

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2327-2336 DOI: 10.6023/cjoc202511006

Abstract( 123) HTML( 0) PDF(673KB)( 50 )

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ARTICLES

Study on Biphonyl Lignans and Their Biological Activities from Magnolia officinalis

Chongyu Shi, Jiayi Chen, Zheyun Lü, Jicheng Shu, Yingqi Zhang, Jianqun Liu

Chinese Journal of Organic Chemistry 2026, 46 (6), pp 2337-2345 DOI: 10.6023/cjoc202512009

Abstract( 113) HTML( 2) PDF(920KB)( 49 )