Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (11): 2583-2601.DOI: 10.6023/cjoc201603037 Previous Articles     Next Articles



刘贵君, 石浩   

  1. 浙江工业大学药学院 杭州 310014
  • 收稿日期:2016-03-23 修回日期:2016-06-19 发布日期:2016-07-08
  • 通讯作者: 石浩
  • 基金资助:


Progress in Chiral Recognition Based on Molecular Tweezers

Liu Guijun, Shi Hao   

  1. College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014
  • Received:2016-03-23 Revised:2016-06-19 Published:2016-07-08
  • Supported by:

    Project supported by the Natural Science Foundation of Zhejiang Province (No.LY13B020013).

Chirality is a common phenomenon in nature. Designing and synthesis of novel artificial receptors to emulate the molecular recognition in living organism has become the challenging forefront of bioorganic chemistry and supramolecular chemistry. Molecular tweezers have been widely applied in chiral molecular recognition and detection for its easily modified structure. Molecular tweezers and their chiral recognition properties detected by spectrometry, chromatography and mass spectrometry are summarized in this paper, and the prospect of molecular tweezers is also discussed.

Key words: molecular tweezers artificial receptor, chiral recognition, spectrometry, chromatography, mass spectrometry