Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (10): 2368-2379.DOI: 10.6023/cjoc201604006 Previous Articles     Next Articles

Reviews

过渡金属催化氧(氮)杂二环烯烃与碳负离子型亲核试剂的不对称开环反应研究进展

仵瑞华, 杨文, 程果, 李玥, 杨定乔   

  1. 华南师范大学化学与环境学院 教育部环境理论化学重点实验室 广州 510006
  • 收稿日期:2016-04-03 修回日期:2016-05-17 出版日期:2016-10-25 发布日期:2016-06-02
  • 通讯作者: 杨定乔,E-mail:yangdq@scnu.edu.cn E-mail:yangdq@scnu.edu.cn
  • 基金资助:

    国家自然科学基金(Nos.21172081,21372090)、广东省自然科学基金重点(No.S2013020013091)和广州市科技计划(No.156300018)资助项目.

Progress in Transition Metal-Catalyzed Asymmetric Ring-Opening Reactions of Oxa(Aza)bicyclic Alkenes with Carbanion Nucleophiles

Wu Ruihua, Yang Wen, Cheng Guo, Li Yue, Yang Dingqiao   

  1. Key Laboratory of Theoretical Chemistry of Environment, Ministry of Education, School of Chemistry and Environment, South China Normal University, Guangzhou 510006
  • Received:2016-04-03 Revised:2016-05-17 Online:2016-10-25 Published:2016-06-02
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos.21172081, 21372090), the Natural Science Foundation of Guangdong Province (No.S2013020013091) and the City of Guangzhou Science and Technology Plan Projects (No.156300018).

The recent progress in transition metal-catalyzed asymmetric ring-opening reactions of oxa(aza)bicyclic alkenes with carbanion nucleophiles is reviewed with focus on the influence of the types of transition metal catalysts, carbanion nucleophiles, ligands, the structures of oxa(aza)bicyclic alkenes, solvents and additives on the asymmetric ring-opening reactions. Moreover, the parties of possible mechanisms for the asymmetric ring-opening reactions are also discussed.

Key words: transition metal catalyst, oxa(aza)bicyclic alkene, carbanion nucleophile, asymmetric ring-opening