Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (2): 492-497.DOI: 10.6023/cjoc201707029 Previous Articles     Next Articles



兰立新, 肖洁, 肖怀秋, 易卫国   

  1. 湖南化工职业技术学院 株洲 412004
  • 收稿日期:2017-07-25 修回日期:2017-10-16 发布日期:2017-10-31
  • 通讯作者: 易卫国
  • 基金资助:


Ultrasonic-Assisted Synthesis of 2-Sulfonyl Nitrogen Heterocyclic Compounds

Lan Lixin, Xiao Jie, Xiao Huaiqiu, Yi Weiguo   

  1. Hunan Chemical Vocational Technology College, Zhuzhou 412004
  • Received:2017-07-25 Revised:2017-10-16 Published:2017-10-31
  • Contact: 10.6023/cjoc201707029
  • Supported by:

    Project supported by the Scientific Research Fund of Hunan Provincial Education Department (No. 15C0464).

A facile and convenient ultrasonic-assisted method for the synthesis of 2-sulfonyl nitrogen heterocyclics has been developed. Using bromo-tris-pyrrolidino-phosphonium hexafluorophosphate (PyBroP) as catalyst, the reactions were carried out under ultrasound irradiation condition at room temperature for 1.0 h, and the 2-sulfonyl nitrogen heterocyclics were obtained in good yields with nitrogen heterocyclic N-oxides and sulfinic acid as raw materials. The reaction has the advantages of good substrate suitability, short reaction times and high yields, which provides a efficient approach for the synthesis of 2-sulfonyl nitrogen heterocyclics and their derivatives.

Key words: 2-sulfonyl nitrogen heterocyclics, nitrogen heterocyclic N-oxides, sulfinic acids, ultrasound-assisted