Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (8): 2174-2181.DOI: 10.6023/cjoc201802012 Previous Articles     Next Articles

Notes

离子液体水溶液中2-甲基氮杂芳烃苄位C(sp3)-H官能化反应

艾锋, 谢宗波, 姜国芳, 季久健, 乐长高   

  1. 东华理工大学应用化学系 南昌 330013
  • 收稿日期:2018-02-07 修回日期:2018-03-16 出版日期:2018-08-25 发布日期:2018-04-13
  • 通讯作者: 乐长高, 谢宗波 E-mail:zhgle@ecit.cn;zbxie@ecit.cn
  • 基金资助:

    国家自然科学基金(Nos.21462001,21262002,21465002)、江西省科技计划项目(No.20161BCB24006)和江西省教育厅科技(Nos.KJLD14050,GJJ150584)资助项目.

Benzylic C(sp3)-H Functionalization Reaction of 2-Methylazaarenes in Ionic Liquid Aqueous Solution

Ai Feng, Xie Zongbo, Jiang Guofang, Ji Jiujian, Le Zhanggao   

  1. Department of Applied Chemistry, East China University of Technology, Nanchang 330013
  • Received:2018-02-07 Revised:2018-03-16 Online:2018-08-25 Published:2018-04-13
  • Contact: 10.6023/cjoc201802012 E-mail:zhgle@ecit.cn;zbxie@ecit.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21462001, 21262002, 21465002), the Science and Technology Projects of Jiangxi Province (No. 20161BCB24006) and the Science and Technology Foundation of the Jiangxi Education Department (Nos. KJLD14050, GJJ150584).

The catalyst-free addition of 2-methylazaarenes benzylic C(sp3)-H to electron-deficient olefins in neutral ionic liquid aqueous solution was reported, and a series of azaarene derivatives were obtained in good yields. This method is easy to operate and the reaction conditions are mild, which not only expands the application of ionic liquid in C(sp3)-H functionalization reaction, but also has positive significance for promoting the development of the green chemistry.

Key words: ionic liquid aqueous solution, electron-deficient olefin, benzylic C(sp3)-H functionalization, 2-methylazaarene