Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (8): 1985-1992.DOI: 10.6023/cjoc201803019 Previous Articles     Next Articles



房智兴, 刘巨艳, 乔艳红   

  1. 天津师范大学化学学院 天津市功能分子结构与性能重点实验室无机-有机杂化功能材料化学省部共建教育部重点实验室 天津 300387
  • 收稿日期:2018-03-14 修回日期:2018-05-05 发布日期:2018-05-24
  • 通讯作者: 刘巨艳
  • 基金资助:


Bromodimethylsulfonium Bromide Catalyzed Synthesis of Pyrazole-Fused Isocoumarins

Fang Zhixing, Liu Juyan, Qiao Yanhong   

  1. Tianjin Key Laboratory of Structure and Performance for Functional Molecule, Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry, Ministry of Education, College of Chemistry, Tianjin Normal University, Tianjin 300387
  • Received:2018-03-14 Revised:2018-05-05 Published:2018-05-24
  • Contact: 10.6023/cjoc201803019
  • Supported by:

    Project supported by the Natural Science Foundation of Tianjin City (No. 12JCZDJC34300), and the College Students' Entrepreneurship Training Program (No. 201447).

A series of pyrazole-fused isocoumarins were synthesized by the reaction of ninhydrin hydrate and arylhydrazones in the presence of bromodimethylsulfonium bromide (BDMS) at room temperature. The reaction has the advantages of mild conditions, simple operation, the ready accessibility of the catalyst, and short reaction times.

Key words: ninhydrin hydrate, arylhydrazones, pyrazole-fused isocoumarins, BDMS