Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (2): 532-537.DOI: 10.6023/cjoc201807024 Previous Articles     Next Articles

Notes

酸酐诱导的2-(1-羟基-1-苯烷基)苯酚一步合成邻酰氧基二芳基烯烃

吕雯雯a, 贺信淳a, 施敏a,b, 王飞军a   

  1. a 华东理工大学化学与分子工程学院 上海 200237;
    b 中国科学院上海有机化学研究所 金属有机化学国家重点实验室 上海 200032
  • 收稿日期:2018-07-16 修回日期:2018-09-04 出版日期:2019-02-25 发布日期:2018-09-26
  • 通讯作者: 王飞军 E-mail:feijunwang@ecust.edu.cn
  • 基金资助:

    国家自然科学基金(No.21372075)和上海浦江人才计划(No.16PJD017)资助项目.

Anhydride Induced One-Pot Synthesis of ortho-Acyloxy Diarylalkenes from 2-(1-Hydroxy-1-arylalkyl)phenols

Lü Wenwenaa, He Xinchunaa, Shi Minaa,b, Wang Feijuna   

  1. a School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237;
    b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Received:2018-07-16 Revised:2018-09-04 Online:2019-02-25 Published:2018-09-26
  • Contact: 10.6023/cjoc201807024 E-mail:feijunwang@ecust.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21372075) and the Shanghai Pujiang Program (No. 16PJD017).

Reaction of 2-(1-hydroxy-1-arylalkyl)phenols with anhydride and NEt3 was reported, providing a practical way to the synthesis of ortho-acyloxy diarylalkenes, which is an important motif in many bioactive compounds and starting materials in many organic synthesis. This reaction can be achieved in one pot reaction under mild conditions in good yields.

Key words: 2-(1-hydroxy-1-arylalkyl)phenols, ortho-acyloxy diarylalkenes, mild conditions, anhydride promoted reaction