Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (2): 475-481.DOI: 10.6023/cjoc201808013 Previous Articles     Next Articles

ARTICLE

钯催化的肉桂基碳酸酯化合物与酰腙的烯丙基胺化反应

刘澜涛a, 陈莹莹a,b, 张安安a, 刘雪a,c, 张丽a, 白静茹a, 李恒c, 毛国梁b   

  1. a 商丘师范学院化学化工学院 商丘 476000;
    b 东北石油大学化学化工学院 大庆 163318;
    c 郑州大学化学与分子工程学院 郑州 450001
  • 收稿日期:2018-08-13 修回日期:2018-09-03 出版日期:2019-02-25 发布日期:2018-09-10
  • 通讯作者: 刘澜涛, 毛国梁 E-mail:liult05@iccas.ac.cn;maoguoliang@nepu.edu.cn
  • 基金资助:

    国家自然科学基金(No.21572126)、河南省高校科技创新人才基金(No.14HASTIT016)和河南省科技创新杰出人才(No.2018JQ0011)资助项目.

Palladium Catalyzed Allylic Amination of Cinnamyl Carbonates with Acyl Hydrazones

Liu Lantaoa, Chen Yingyingaa,b, Zhang An'ana, Liu Xuea,c, Zhang Lia, Bai Jingrua, Li Hengc, Mao Guoliangb   

  1. a College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000;
    b College of Chemistry and Chemical Engineering, Northeast Petroleum University, Daqing 163318;
    c College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001
  • Received:2018-08-13 Revised:2018-09-03 Online:2019-02-25 Published:2018-09-10
  • Contact: 10.6023/cjoc201808013 E-mail:liult05@iccas.ac.cn;maoguoliang@nepu.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21572126), the Program for Science & Technology Innovation Talents in Universities of Henan Province (No. 14HASTIT016) and the Program of Science and Technology Innovation Talents of Henan Province (No. 2018JQ0011).

Allylic amines moiety exists extensively in natural products, medicines and functional materials. In addition, they are also a kind of versatile building blocks for organic synthesis. Using CH3CN as solvent, the palladium catalyzed allyl amination of cinnamyl carbonate and acylhydrazone compounds was realized under argon. The linear product was formed selectively and the up to 99% yield was obtained. The reaction has features of base free, mild reaction condition, simple operation and broad substrate scope.

Key words: paladium catalysis, allylic amination, cinnamyl carbonate