Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (5): 1450-1455.DOI: 10.6023/cjoc201812014 Previous Articles     Next Articles



方霄龙a,b, 段宁a, 章敏a, 张春燕b, 刘睿b, 朱红平b   

  1. a 池州学院化学与材料工程学院 池州 247000;
    b 厦门大学化学化工学院 固体表面物理化学国家重点实验室 醇醚酯清洁生产国家工程实验室 厦门 361005
  • 收稿日期:2018-12-10 修回日期:2019-01-10 发布日期:2019-01-31
  • 通讯作者: 方霄龙, 朱红平;
  • 基金资助:


Homogeneous Catalytic Hydrogenation of Dimethyl Malonate into Methyl 3-Hydroxypropanoate

Fang Xiaolonga,b, Duan Ninga, Zhang Mina, Zhang Chunyanb, Liu Ruib, Zhu Hongpingb   

  1. a College of Chemistry and Materials Engineering, Chizhou University, Chizhou 247000;
    b State Key Laboratory of Physical Chemistry of Solid Surfaces, National Engineering Laboratory for Green Chemical Productions of Alcohols-Ethers-Esters, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005
  • Received:2018-12-10 Revised:2019-01-10 Published:2019-01-31
  • Contact: 10.6023/cjoc201812014;
  • Supported by:

    Project supported by the National Natural Science Foundation for Young Scientists of China (No. 21802010), the Natural Science Foundation of Anhui Province (No. 1808085QB48), and the Starting Grants for Young Teachers of Chizhou University (No. 2018YJRC001).

Ruthenium acetylacetonate and aminophosphine ligand were selected as the catalyst system and applied to the catalytic hydrogenation of dimethyl malonate into methyl 3-hydroxypropanoate. With the focus on the catalytic efficiency, the important factors with significant influences on the dimethyl malonate conversion and methyl 3-hydroxypropanoate selectivity were well discussed, including the structure and dosage of the ligand, temperature, reaction time, solvent, and so on. The results revealed that catalyst system of ruthenium acetylacetonate and o-(diphenylphosphino)aniline ligand could obtain significant catalytic results. Under the optimal reaction conditions, this catalyst system can also be applied to catalytic hydrogenation of some other esters with high efficiency.

Key words: ruthenium acetylacetonate, o-(diphenylphosphino)aniline, dimethyl malonate, methyl 3-hydroxypropanoate