Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (5): 1333-1343.DOI: 10.6023/cjoc201812022 Previous Articles     Next Articles



苏瀛鹏, 冯亚威, 曹林丹, 薛文轩, 石娅, 常兵兵, 黄丹凤, 王克虎, 胡雨来   

  1. 西北师范大学化学化工学院 兰州 730070
  • 收稿日期:2018-12-12 修回日期:2019-02-13 发布日期:2019-02-22
  • 通讯作者: 苏瀛鹏
  • 基金资助:


Triphenylphosphine Catalyzed Lu's[3+2] Annulation of Aurones and Alkenoates: Constructing of Spiro[1-benzofuran-3-one-2,5'-cyclopentene] Polycyclic Compounds

Su Yingpeng, Feng Yawei, Cao Lindan, Xue Wenxuan, Shi Ya, Chang Bingbing, Huang Danfeng, Wang Ke-Hu, Hu Yulai   

  1. College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070
  • Received:2018-12-12 Revised:2019-02-13 Published:2019-02-22
  • Contact: 10.6023/cjoc201812022
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21502154, 21362033) and the Gansu Provincial Science and Technology Program (No. 17JR5RA073).

The PPh3 catalyzed Lu's[3+2] annulation of aurones with alkenoates has been developed to form spiro-[1-ben-zofuran-3-one-2,5'-cyclopentene] polycyclic moiety. The usefulness of this strategy has been demonstrated by the use of a wide variety of substrates to give desired polycyclic compounds in high yield under mild and simple reaction condition. This methodology research offered a fine entry for synthesis of natural product applanatumin A and its analogues.

Key words: aurones, alkenoate, PPh3, Lu's[3+2] annulation