Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (6): 1625-1629.DOI: 10.6023/cjoc201911023 Previous Articles     Next Articles

Special Issue: 有机硅化学合辑


葛浩程, 杜科莹, 盛卫坚   

  1. 浙江工业大学化学工程学院 杭州 310014
  • 收稿日期:2019-11-15 修回日期:2020-03-10 发布日期:2020-03-31
  • 通讯作者: 盛卫坚

Synthesis of β,β-Dichloro-α,β-unsaturated Ketones by Trichloro-methyl Radical Addition/Elimination of Enol Silyl Ethers

Ge Haochen, Du Keying, Sheng Weijian   

  1. College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014
  • Received:2019-11-15 Revised:2020-03-10 Published:2020-03-31

Using di-tert-butyl peroxide (DTBP) as oxidant, chloroform or carbon tetrachloride as trichloromethyl radical source and reaction solvent, enol silyl ethers derived from aryl ketone was transferred to β,β-dichloro-α,β-unsaturated ketone by trichloromethyl radical addition/elimination. The conditions are mild with avoiding the use of metal catalysts, and the enol silyl ethers substrate has good universality.

Key words: trichloromethyl radical, enol silyl ethers, β,β-dichloro-α,β-unsaturated