Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (8): 2185-2194.DOI: 10.6023/cjoc202005017 Previous Articles     Next Articles

ACCOUNT

路易斯碱-硼自由基在硼化反应、自由基催化和还原反应中的应用

靳继康, 夏慧敏, 张凤莲, 汪义丰   

  1. 中国科学技术大学化学系 合肥 230026
  • 收稿日期:2020-05-07 修回日期:2020-05-19 出版日期:2020-08-25 发布日期:2020-05-29
  • 通讯作者: 汪义丰 E-mail:yfwangzj@ustc.edu.cn
  • 基金资助:
    国家自然科学基金(Nos.21672195,21702201,21971226)和中央高校基本科研业务费专项资金(No.WK2060190082)资助项目.

Lewis-Base Boryl Radicals Enabled Borylation, Radical Catalysis and Reduction Reactions

Jin Jikang, Xia Huimin, Zhang Fenglian, Wang Yifeng   

  1. Department of Chemistry, University of Science and Technology of China, Hefei 230026
  • Received:2020-05-07 Revised:2020-05-19 Online:2020-08-25 Published:2020-05-29
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Nos. 21672195, 21702201, 21971226) and the Fundamental Research Funds for the Central Universities (No. WK2060190082).

Free radical reactions represent an efficient and significant tool to construct organic molecules by taking advantages of the high-efficiency, remarkable selectivity and good functional groups tolerance. Lewis-base boryl radicals are a class of species that possess unique structures and chemical reactivity, and a variety of synthetic applications have been developed. This account summarizes the research advances in this research field mainly contributed by our group. The results include Lewis-based boryl radicals enabled borylation reactions, Lewis-based boryl radicals-catalyzed new reactions, and Lewis-based boryl radicals promoted reduction reactions. These reactions feature mild reaction conditions, good functional groups compatibility, high yields, and excellent chemo-, regio-, and stereo-selectivities.

Key words: Lewis-base boryl radicals, radical borylation reactions, radical catalysis, radical reduction reactions, free radical chemistry