Lewis-Base Boryl Radicals Enabled Borylation, Radical Catalysis and Reduction Reactions

doi:10.6023/cjoc202005017

Abstract

Free radical reactions represent an efficient and significant tool to construct organic molecules by taking advantages of the high-efficiency, remarkable selectivity and good functional groups tolerance. Lewis-base boryl radicals are a class of species that possess unique structures and chemical reactivity, and a variety of synthetic applications have been developed. This account summarizes the research advances in this research field mainly contributed by our group. The results include Lewis-based boryl radicals enabled borylation reactions, Lewis-based boryl radicals-catalyzed new reactions, and Lewis-based boryl radicals promoted reduction reactions. These reactions feature mild reaction conditions, good functional groups compatibility, high yields, and excellent chemo-, regio-, and stereo-selectivities.

Key words: Lewis-base boryl radicals, radical borylation reactions, radical catalysis, radical reduction reactions, free radical chemistry

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Jin Jikang, Xia Huimin, Zhang Fenglian, Wang Yifeng. Lewis-Base Boryl Radicals Enabled Borylation, Radical Catalysis and Reduction Reactions[J]. Chinese Journal of Organic Chemistry, 2020, 40(8): 2185-2194.

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