Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (10): 4007-4013.DOI: 10.6023/cjoc202105050 Previous Articles Next Articles
ARTICLES
芦军, 梁仁校, 贾义霞*(
)
收稿日期:2021-05-29
修回日期:2021-07-31
发布日期:2021-08-17
通讯作者:
贾义霞
基金资助:
Jun Lu, Renxiao Liang, Yixia Jia()
Received:2021-05-29
Revised:2021-07-31
Published:2021-08-17
Contact:
Yixia Jia
Supported by:Share
Jun Lu, Renxiao Liang, Yixia Jia. Copper-Catalyzed Intramolecular Dearomative Arylation of Naphthylamines[J]. Chinese Journal of Organic Chemistry, 2021, 41(10): 4007-4013.
| Entry | Solvent | Base | Ligand | Yieldb/% |
|---|---|---|---|---|
| 1 | THF | tBuOLi | 1,10-Phen | 20 |
| 2 | Dioxane | tBuOLi | 1,10-Phen | 50 |
| 3 | Toluene | tBuOLi | 1,10-Phen | 23 |
| 4 | DMSO | tBuOLi | 1,10-Phen | 92 |
| 5 | DMSO | Et3N | 1,10-Phen | NR |
| 6 | DMSO | K3PO4 | 1,10-Phen | 85 |
| 7 | DMSO | K2CO3 | 1,10-Phen | 89 |
| 8 | DMSO | tBuOLi | IMes | 27 |
| 9 | DMSO | tBuOLi | L-Proline | 29 |
| 10 | DMSO | tBuOLi | — | 25 |
| 11c | DMSO | tBuOLi | 1,10-Phen | 66 |
| 12d | DMSO | tBuOLi | 1,10-Phen | 72 |
| 13e | DMSO | tBuOLi | 1,10-Phen | NR |
| Entry | Solvent | Base | Ligand | Yieldb/% |
|---|---|---|---|---|
| 1 | THF | tBuOLi | 1,10-Phen | 20 |
| 2 | Dioxane | tBuOLi | 1,10-Phen | 50 |
| 3 | Toluene | tBuOLi | 1,10-Phen | 23 |
| 4 | DMSO | tBuOLi | 1,10-Phen | 92 |
| 5 | DMSO | Et3N | 1,10-Phen | NR |
| 6 | DMSO | K3PO4 | 1,10-Phen | 85 |
| 7 | DMSO | K2CO3 | 1,10-Phen | 89 |
| 8 | DMSO | tBuOLi | IMes | 27 |
| 9 | DMSO | tBuOLi | L-Proline | 29 |
| 10 | DMSO | tBuOLi | — | 25 |
| 11c | DMSO | tBuOLi | 1,10-Phen | 66 |
| 12d | DMSO | tBuOLi | 1,10-Phen | 72 |
| 13e | DMSO | tBuOLi | 1,10-Phen | NR |
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