Interaction between the targeted liposomes of containing linoleic piatinum and tumour cell membrans

Chin. J. Org. Chem. ›› 1995, Vol. 15 ›› Issue (5): 505-510. Previous Articles Next Articles

Original Articles

亚油酸铂靶向脂质体与癌细胞膜相互作用的电子自旋共振研究

张静;孙润广;孙玉晴;郝爱民

陕西师范大学实验中心;中国科学院理论物理研究所

发布日期:1995-10-25

Interaction between the targeted liposomes of containing linoleic piatinum and tumour cell membrans

ZHANG JING;SUN RUNAN;SUN YUQING;HAO AIMIN

Published:1995-10-25

Abstract

The interaction between the targeted liposome of containing linoleic platinum and tumor cell membranes was studied by method of 3- maleimide-2, 2, 5, 5-tetramethyl-1-pyrrolidinyloxyl spin label (MSL). The targeted liposome of containing linoleic platinum effects on ESR spectrum of tumor cells labeled with MSL. In the presence of linoleic platinum the ratios of W and S of breast cancer cell membranes and S180 cell membranes labeled with MSL were changed, The results indicate linoleic platinum can react with mercapto groups on the proteins of tumor cell membranes and change the conformations of cell membrane proteins.

Key words: LIPOSOME, ANTICARCINOGEN, ELECTRON SPIN RESONANCE, BREAST CANCER

CLC Number:

O627

Cite this article

ZHANG JING;SUN RUNAN;SUN YUQING;HAO AIMIN. Interaction between the targeted liposomes of containing linoleic piatinum and tumour cell membrans[J]. Chin. J. Org. Chem., 1995, 15(5): 505-510.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	YANG Guang, ZHU Hua, SHEN Yu-Mei. Synthesis of Novel Polyethylene Glycol (PEG)-Cyclofenil as Molecu-lar Probe of Estrogen Receptor β [J]. Chin. J. Org. Chem., 2011, 31(05): 715-723.
[2]	Zhu, Huaa,b Huang, Lilianga,b Zhang, Chunchuna,b Xu, Jiaa Shen, Yumei*,a. Synthesis of Cyclofenil Rhenium Tricarbonyl Conjugates [J]. Chin. J. Org. Chem., 2009, 29(9): 1450-1456.
[3]	Han Guangfan;Wang Jinjun;Jiang Guiji. Synthesis of Chroman-4-ono[2,3-b]quinolinone Derivatives [J]. Chin. J. Org. Chem., 2003, 23(9): 1004-1007.
[4]	Zhao Jin;Song Jinyong;Wang Chaojie. Synthesis of 4-N-Solanesylamino-benzoic Acid Glycosyl Esters [J]. Chin. J. Org. Chem., 2003, 23(7): 714-716.
[5]	Tian Laijin;Yu Qingsen;Liu Xijie;Shang Zhicai;Wang Tao;Zhao Wenna. Synthesis and Structural Characterization of 3- Trichlorostannylpropionates and Their Complexes [J]. Chin. J. Org. Chem., 2003, 23(5): 441-446.
[6]	Liu Jianli. Biomimetic Synthesis of Camptothecin: A Story of Quarter Century [J]. Chin. J. Org. Chem., 2003, 23(5): 432-437.
[7]	Yin Handong;Wang Chuanhua;Ma Chunlin. Synthesis, Anti-tumour Properties and Crystal Structure of Bis { oxo-bis[ (2-furylcarboxylato)dibenzyltin(IV) ]} [J]. Chin. J. Org. Chem., 2003, 23(5): 475-478.
[8]	Peng Bin;Sun LiJuan;Chang WeiXing;Xie QinLan. Syntheses and Study of Diorganotin Ferrocenoates [J]. Chin. J. Org. Chem., 2003, 23(4): 344-349.
[9]	Ren YuJie;Jia CuiYing;Zhao YuMei;Li Ping;Li Hua;Chen HuiLin. Synthesis and Properties of (Z)-1-[2-(Tribenzyistannyl) vinyl]-l- cycioheptanol and Its Benzylhalostannyl Derivatives [J]. Chin. J. Org. Chem., 2003, 23(4): 372-374.
[10]	Wu Yaowen;Jiang Yuyang;Fu Hua;Yang Jie;Zhao Yufen. Nucleoside Analogues as Anticancer Agents [J]. Chin. J. Org. Chem., 2003, 23(10): 1091-1098.
[11]	She Zhigang;Hu Guping;Wu Yaowen;Lin Yongcheng. Study on the methanolysis of the sulphated polysaccharide hal-a from haliotis diverisicolor reeve [J]. Chin. J. Org. Chem., 2002, 22(5): 367-370.
[12]	Liu Yanqin;Zhang Huijuan;Han Shitian. Synthesis and antitumor activity of 5-fluorouracil-porphyrin compounds [J]. Chin. J. Org. Chem., 2002, 22(4): 279-282.
[13]	Yin Handong;Wang Chuanhua;Ma Chunlin;Wang Yong;Zhang Rufen. Synthesis and crystal structure of tribenzyltin dithiopiperidylcarbamate and dibenzyltin bisdithiopiperidycarbamate [J]. Chin. J. Org. Chem., 2002, 22(3): 183-188.
[14]	Shi Daqing;Wang Xiangshan;Tu Shujiang. Synthesis of 4H-Chromene Derivatives Catalyzed by KF/Al_2O_3 [J]. Chin. J. Org. Chem., 2002, 22(12): 1053-1056.
[15]	Liu Fulong;Jiang Tao;Zuo Daishu;Qi Xin;Zhan Xiaolin. Synthesis of 5,6-dehydronorcantharidin derivatives of susbstituted aromatic amine and their anti-tumor activities [J]. Chin. J. Org. Chem., 2002, 22(10): 761-767.

亚油酸铂靶向脂质体与癌细胞膜相互作用的电子自旋共振研究

Interaction between the targeted liposomes of containing linoleic piatinum and tumour cell membrans

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments