Asymmetric synthesis of  (2S)-2-brom-1-(6'-methoxy-2'-naphthyl)propan- 1-one

Chin. J. Org. Chem. ›› 1999, Vol. 19 ›› Issue (1): 93-96. Previous Articles Next Articles

Original Articles

(2S)-(+)-2-溴-1-(6'-甲氧基-2'-萘基)丙-1-酮的不对称合成

胡艾希;范国枝;赵海涛

湖南大学化学化工学院

发布日期:1999-02-25

Asymmetric synthesis of (2S)-2-brom-1-(6'-methoxy-2'-naphthyl)propan- 1-one

Hu Aixi;Fan Guozhi;Zhao Haitao

Published:1999-02-25

Abstract

(2S)-2-Brom-1-(6'-methoxy-2'-naphthyl)propan-1-one was systhsized by acetalization, asymmetric bromination, hydrolysis of 6-methoxy-2- propionyl naphthalene using (2R, 3R)-dimethyl tartrate as chiral auxiary, cupricbromide as the brominating agent with 94% total yield.

Key words: ACETONE P, BROMINE COMPOUNDS, ELEMENTAL ANALYSIS, NAPHTHALENE P, TARTARIC ACID P, METHOXY GROUP, NMR SPECTROMETRY, MASS SPECTROGRAPHY

CLC Number:

O621

Cite this article

Hu Aixi;Fan Guozhi;Zhao Haitao. Asymmetric synthesis of (2S)-2-brom-1-(6'-methoxy-2'-naphthyl)propan- 1-one[J]. Chin. J. Org. Chem., 1999, 19(1): 93-96.

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(2S)-(+)-2-溴-1-(6'-甲氧基-2'-萘基)丙-1-酮的不对称合成

Asymmetric synthesis of (2S)-2-brom-1-(6'-methoxy-2'-naphthyl)propan- 1-one

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