Chin. J. Org. Chem. ›› 2010, Vol. 30 ›› Issue (06): 809-815. Previous Articles     Next Articles

Reviews

电喷雾质谱法研究不对称催化反应进展

赵志雄,姚胜军,王昊阳*,郭寅龙*   

  1. 中国科学院上海有机化学研究所 上海质谱中心 上海 200032
  • 收稿日期:2009-06-30 修回日期:2009-12-18 出版日期:2010-06-25 发布日期:2010-02-23
  • 通讯作者: 王昊阳 E-mail:haoyangwang@mail.sioc.ac.cn

Progress in ESI-MS Study for the Catalytic Asymmetric Reactions

ZHAO Zhi-Xiong, YAO Sheng-Jun, WANG Hao-Yang, GUO Yin-Long   

  1. Shanghai Mass Spectrometry Center, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, Shanghai 200032
  • Received:2009-06-30 Revised:2009-12-18 Online:2010-06-25 Published:2010-02-23
  • Contact: WANG Hao-Yang E-mail:haoyangwang@mail.sioc.ac.cn

The utility of ESI-MS for studying the enantioselectivity of catalytic asymmetric reactions by measurement of the ee value of product or the different intensity of reactive intermediates/complexes involved in the asymmetric reactions, and the further evaluating and screening chiral catalysts would be discussed in this review.

Key words: mass spectrometry, electrospray ionization method, catalytic asymmetric reaction, ee value, reactive intermediate