Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (9): 1730-1742.DOI: 10.6023/cjoc201403040 Previous Articles     Next Articles


甘春芳, 盛海兵, 戚斌斌, 杨雷, 赵丹丹, 黄燕敏, 崔建国   

  1. 广西师范学院化学与生命科学学院, 南宁 530001
  • 收稿日期:2014-03-18 修回日期:2014-04-21 发布日期:2014-05-07
  • 通讯作者: 崔建国
  • 基金资助:

    广西省自然科学基金(Nos. 2012GXNSFAA053018, 2012GXNSFAA053018)及广西高等科学技术研究(No. 200103YB067)资助项目.

Recent Advance of Synthesis and Bioactivities for Steroids with Special Steroidal Nucleus

Gan Chunfang, Sheng Haibing, Qi Binbin, Yang Lei, Zhao Dandan, Huang Yanmin, Cui Jianguo   

  1. College of Chemistry and Life Science, Guangxi Teachers Education University, Nanning 530001
  • Received:2014-03-18 Revised:2014-04-21 Published:2014-05-07
  • Supported by:

    Project supported by the Natural Science Foundation of Guangxi Province (Nos. 2012GXNSFAA053018, 2012GXNSFAA053018) and the Scientific and Technology Research Funding of Guangxi University (No. 200103YB067).

By changing the structure of steroidal nucleus, or introducing different functional groups into steroids, some steroidal compounds with various bioactivities might be obtained. In this paper, according to the different types of steroid nucleus structure, combining with the results of our research in steroids with special steroidal nucleus, the advance of synthesis and biological activities for A-nor steroids, B-nor steroids and C-nor-D-homo-steroids is discussed in recent years, and the development trend and application prospect are forecasted.

Key words: special steroidal nucleus, A-nor steroids, B-nor steroids, C-nor-D-homo-steroids