Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (11): 2739-2742.DOI: 10.6023/cjoc201604055 Previous Articles     Next Articles

Notes

展毛大渡乌头全草中的新二萜生物碱

徐文亮, 单连海, 黄帅, 李遂焰, 周先礼   

  1. 西南交通大学生命科学与工程学院 成都 610031
  • 收稿日期:2016-04-26 修回日期:2016-06-21 发布日期:2016-07-13
  • 通讯作者: 周先礼 E-mail:xxbiochem@163.com
  • 基金资助:

    国家自然科学基金(No.81274193)、四川省小分子天然药物创新团队(No.15TD0048)、中央高校基本科研业务费专项(No.2682015YXZT03)和西南交通大学2015年研究生创新实验实践(No.YC201510102)资助项目.

New Ditetpenoid Alkaloid from the Whole Plant of Aconitum franchetii var. villosulum

Xu Wenliang, Shan Lianhai, Huang Shuai, Li Suiyan, Zhou Xianli   

  1. School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031
  • Received:2016-04-26 Revised:2016-06-21 Published:2016-07-13
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No.81274193),the Small Molecule Natural Medicine Innovation Team (No.15TD0048),the Fundamental Research Funds for Central Universities (No.2682015YXZT03) and the Southwest Jiaotong University Graduate Students Creative Experiment (No.YC201510102).

A new aconitine-type diterpenoid alkaloid, villosutine (1), was isolated from the whole plant of Aconitum franchetii var. villosulum, together with four other known aconitine-type diterpenoid alkaloids, one known pyro-type diterpenoid alkaloid and five known franchetine-type diterpenoid alkaloids. Their structures were elucidated on the basis of extensive spectroscopic analy-sis, including HR-ESIMS, 1D and 2D NMR experiments.

Key words: aconitum, Aconitum franchetii var. villosulum, diterpenoid alkaloid, villosutine