Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (6): 1582-1584.DOI: 10.6023/cjoc201701035 Previous Articles     Next Articles

Notes

三氟甲磺酸酯的高效合成(英文)

郑东青a,b, 马海燕b, 丁凯a   

  1. a. 中国科学院上海有机化学研究所 天然产物合成有机化学重点实验室 上海 200032;
    b. 华东理工大学化学系 上海 200237
  • 收稿日期:2017-01-18 修回日期:2017-01-20 发布日期:2017-01-20
  • 通讯作者: 马海燕,丁凯 E-mail:haiyanma@ecust.edu.cn;dingkai@mail.sioc.ac.cn
  • 基金资助:

    国家自然科学基金(No.20902098)资助项目.

A Practical Synthesis of Trifluoromethanesulfonate Esters

Zheng Dongqinga,b, Ma Haiyanb, Ding Kaia   

  1. a. CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032;
    b. Department of Chemistry, East China University of Science and Technology, Shanghai 200237
  • Received:2017-01-18 Revised:2017-01-20 Published:2017-01-20
  • Contact: 10.6023/cjoc201701035 E-mail:haiyanma@ecust.edu.cn;dingkai@mail.sioc.ac.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 20902098).

A practical synthesis of trifluoromethanesulfonate esters by reaction of orthoformate esters with triflic anhydride is described. The solvent-free method featured mild condition, short time, high yield, simple operation and broad substrate scope. The in situ generated trifluoromethanesulfonate ester is highly reactive alkylating agent, providing triflate ionic liquid in excellent yield via a one-pot procedure.

Key words: trifluoromethanesulfonate ester, orthoester, triflic anhydride, one-pot alkylation