Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (3): 747-753.DOI: 10.6023/cjoc201808022 Previous Articles     Next Articles


不饱和螺环缩酮的合成及对桔小实蝇(Bactrocera dorsalis)性引诱活性与构效关系研究

李九一a, 陈立b, 尹标林a   

  1. a 华南理工大学化学与化工学院 广东省功能分子工程重点实验室 广州 510640;
    b 中国科学院动物研究所 农业虫害鼠害综合治理研究国家重点实验室 北京 100101
  • 收稿日期:2018-08-20 修回日期:2018-09-29 发布日期:2018-11-12
  • 通讯作者: 尹标林
  • 基金资助:


Synthesis, Biological Evaluation, and Structure-Activity Relationship Study of Unsaturated Spiroacetals as Potential Sex Attractants to Oriental Fruit Flies (Bactrocera dorsalis)

Li Jiuyia, Chen Lib, Yin Biaolina   

  1. a Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640;
    b State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101
  • Received:2018-08-20 Revised:2018-09-29 Published:2018-11-12
  • Contact: 10.6023/cjoc201808022
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21572068, 21871094).

Spiroacetal motif is widely distributed in many bioactive natural products of different origins and essentially contributes to various bioactivities. In this paper, two series of spiroacetals were synthesized and biologically evaluated as insect sex attractant towards oriental fruit flies (Bactrocera dorsalis) using methyleugenol as the standard. Biological evaluation demonstrated that a large part of the tested compounds triggered apparent electrophysiological responses from both male and female fruit flies. The stereochemistry of the spiroacetals and the substitution on their phenyl rings influenced the responses to some degree.

Key words: spiroacetals, sex attractant, oriental fruit fly (Bactrocera dorsalis), electroantennogram response