In this work the oxidation reactions of quinazolone-4 with chromic acid, potassium permanganate, peracetic acid, and perbenzoic acid have been studied.When quinazolone was heated with chromic anhydride in glacial acetic acid, quinazolone chromate(Ⅰ) was isolated as previously reported in literature.Oxidation of quinazolone with potassium permanganate in neutral or alkaline solutions gave quinazolone oxalate (Ⅲ) and with the same reagent in acidic solutions produced benzoylene urea (2,4-dihydroxyquinazoline, Ⅱ).Carbon dioxide and ammonia were always liberated in these experiments, but no other oxidation product was isolated.