Numerous well-known drugs acting on various nerve systems are phenyl,benzyl or benzhydryl esters,ketones or ethers carrying a β-amino substituted carbon chain. Procaine, Trasentine,Amidone and Benadryl are examples of such types. It appears interesting to see if the corresponding sulphones would also be pharmacologically active. β-Aminosulphones are the oxidation products of the corresponding sulphides. Moreover,the β-aminosulphides could be regarded as the ring-cleaved derivatives of phenothiazine (Ⅰ),and the latter compound is the nucleus of a number of medicinal agents such as promethazine and chlorpromazine. A number of β-aminosulphides and β-aminosulphones are therefore prepared in the present work for pharmacological examinations.