Acta Chimica Sinica ›› 1963, Vol. 29 ›› Issue (1): 8-18. Previous Articles     Next Articles

氯丙嗪裂环类似物的合成

宗汝实, 嵇汝运   

  1. 中国科学院药物研究所
  • 投稿日期:1962-04-02 发布日期:2013-06-03

THE SYNTHESIS OF SOME RING-CLEFT ANALOGUES OF CHLORPROMAZINE

TSUNG JU-SHTH, KYI ZU-YOONG   

  1. Institute of Materia Medica, Academia Sinica, Shanghai
  • Received:1962-04-02 Published:2013-06-03

With the object of ascertaining whether ring cleavage of chlorpromazine,one of the most widely used drugs in psychiatry,would lead to products retaining the tranquilizing activity and yet avoiding the side effects of the parent compound,we have synthesized in the present work a number of N-(β-p-chlorophenylmercaptoethyl)-y-dialkylaminopropylamines and N-(β-p-phenvlmercaptoethyl)-N-(γ-dialkylaminopropyl)-anilines.