Five aoylphlorogluoinol derivatives named agrimol-A,-B,-C,-D, and -E have been isolated from the medicinal plant, Shian-Ho-Tsao [Agrimonia pilosa Ledeb (Rosaceae)].The moleonlar formulae found by means of elementary analysis and mass spectra are shown as follows: agrimol-A, C₃₇H₄₆O₁₂; agrimol-B, C₃₇H₄₈O₁₂; agrimol-C, C₃₆H₄₄O₁₂; agrimol-D, C₃₅H₄₂O₁₂ and agrimol-E, C₃₃H₃₈O₁₂ The structure of agrimol-C is proved to be tris-ψ-aspidinol nBnBnB (III) with the aid of UV, IR, NMR, MS spectral analyses, and through chemical identification of its alkali degradation products.The proposed structure of agrimol-C has been confirmed by chemical synthesis.