Acta Chimica Sinica ›› 1976, Vol. 34 ›› Issue (2): 149-152. Previous Articles    

dl—前列腺素F2a的合成

前列腺素合成组   

  1. 中国科学院上海有机化学研究所
  • 投稿日期:1975-11-13 发布日期:2013-06-03

THE SYNTHESES OF dl-PROSTAGLANDIN F2a

THE PROSTAGLANDIN SYNTHESIS GROUP Shanghai   

  1. Institute of Organic Chemistry, Academia Sinica
  • Received:1975-11-13 Published:2013-06-03

dl-Prostaglandin F(Ⅹ) was synthesized from cyclopentadiene via a ten-step process.dl-Diol(Ⅱa) was epoxidized sterospecifically by peraoids to the dl-epozide(Ⅲa),the structure of whioh was established by oxidation to the known compound (ⅩⅤ).However,the diacetate(Ⅱb) reaoted with peracids to give a 1:1 mixture of cis-syn-cis and cis-anti-cis dl-isomers (Ⅲb) and (ⅩⅡ).