Gastrodin (1), a phenolic glucoside was isolated from Gastrodia elata Bl. It showed significant sedative and hypnotic activities in mice. The synthetic specimen exhibits the same activities and m. p., UV, IR, NMR data as natural gastrodin does. The preent paper describes the syntheses of gastrrodin and related compounds [2-methoxy-4-hydro-xymethylphenyl-β-D-glucopyranoside (2), 2-methogy-4-formylphenyl-β-D-gluco-pyranoside (3) and 4-formylphenyl-β-D-glucopyranoside (4)].