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Acta Chimica Sinica ›› 1980, Vol. 38 ›› Issue (3): 251-256. Previous Articles     Next Articles

5α-雄甾-3, 17-双酮用节杆菌转化

周维善, 沈季铭   

  1. 中国科学院上海有机化学研究所
  • 投稿日期:1978-05-18 发布日期:2013-06-03

MICROBIOLOGICAL TRANSFORMATION OF 5α-ANDROSTANE-3, 17-DIONE BY CORYNEBACTERIUM SIMPLEX

ZHOU WEI-SHAN, SHEN JI-MING   

  1. Shanghai Institute of Organic Chemistry, Academia Sinica
  • Received:1978-05-18 Published:2013-06-03

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Incubation of 5α-androstane-3, 17-dione with Corynebacterium simplex afforded four 9α-hydroxylated produots (2~5),among which 9α-hydroxy-△1-5α-androsten)-3, 17-dione (3) was the major produot. The structures of the four compounds wero assigned by means of spectroscopic evidences and chemical correlations.