The use of cyclodextrin as host to provide a special environment for organic reactions and for enzyme models has received considerable attention in recent years. However, in cyclodextrin both the size and length of the hydrophobic cavity are fixed. In this paper, another type of inclusion with sodium carboxymethylamylose (Na-CMA) playing the role of the host which provides a cavity with the characteristics similar to that of cyclodextrin but with more flexibility in itg size and length was described. The substrates with hydrophobic long hydrocarbon chain used were: cetyltrimethylammonium chloride (CTACl);lauryltrimethylammonium iodide (LTAI) and sodium laurylsulfate (NaLS).