Acta Chimica Sinica ›› 1981, Vol. 39 ›› Issue (5): 433-437. Previous Articles     Next Articles

陵水暗罗有效成分的研究 Ⅰ.天然含锌化合物暗罗素的分离及结构

韩公羽1, 徐炳祥1, 王肖鹏1, 刘明珠1, 许学余1, 孟利宁1, 陈仲良2, 朱大元2   

  1. 1. 第二军医大学训练部中草药研究组 上海;
    2. 中国科学院上海药物研究所
  • 投稿日期:1979-06-27 发布日期:2013-06-03

STUDY ON THE ACTIVE PRINCIPLE OF POLYALTHIA NEMORALIS Ⅰ. THE ISOLATION AND IDENTIFICATION OF NATURAL ZINC COMPOUND

HAN GUNG-YU1, XU BING-XIANG1, WANG XIAO-PENG1, LIU MING-ZHU1, XU XUE-YU1, MENG LI-NING1, CHEN ZHONG-LIANG2, ZHU DA-YUAN2   

  1. 1. Second Military Medical College, Shanghai;
    2. Shanghai Institute of Materia Medica, Academia Sinica
  • Received:1979-06-27 Published:2013-06-03

A zinc containing organic compound was isolated from the Chinese medicinal plant Plasmodium berghei A.et DC.(0.0008% yield) and was identified as zinc salt of 2-mercaptopyridine-N-oxide by means of NMR, IR,UV and high resolution MS spectra and confirmed by chemical synthesis.The compound was shown to exhibit antimalarial activity againat Plasmodium berghei.